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. 2019 Oct;61(4):450–458. doi: 10.1165/rcmb.2018-0220OC

Figure 6.

Figure 6.

CDHR3 rs6967330 genotype affects ciliogenesis during differentiation of human BEC-ALI cultures. (A) Bar graph represents fluorescent bead tracking velocity (pixels/frame) as a measurement of cilia beat function in differentiating BECs with A/A or G/G genotype at Days 14, 21, and 24 of ALI culture. (B–F) Curves illustrate mRNA expression of FOXJ1 (B), CDHR3 (C), C-MYB (myeloblastosis family transcription factor) (D), MUC5AC (mucin 5AC, oligomeric mucus/gel-forming) (E), and SCGB1A1 (secretoglobin family 1A member 1) (F) in A/A and G/G genotype–differentiating BEC-ALI cultures over 28 days. *P < 0.05 and **P < 0.001.