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S100A9−/− mice produce more IL-13 and serum IgE in response to airway allergen challenge. (A–C) The level of BAL type 2 cytokines, IL-13 (A) and IL-5 (B), and serum IgE (C) were determined by ELISA. Data are combined from two separate experiments and include 11–17 Alt-challenged and eight or nine mock-challenged mice per genotype. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. Data with error bars represent mean ± SEM.
