Fig. 1.

Study design. A population of Swiss-Webster mice (four animals/cage, five cages/group) were initially given Neomycin for 5 days to clear their gut microbiota. Then all mice were given fecal transplants (FT) from either Swiss-Webster mice or Neotoma albigula for 6 days. Some groups were then treated with antibiotics (Abx) and/or were maintained on a low fat/low sugar diet (LFLS) or switched to a high fat/high sugar diet (HFHS) for 12 days. Urine and feces were collected for creatinine, oxalate, and microbial assays at 3-day intervals