Fig. 2.

Potential metabolic interactions of Ca. A. hamiconexum CG and Ca. H. crystalense. The metabolism of the host complements the metabolism of the symbiont at various stages. The figure depicts three different options for metabolite transfer between the host and the symbiont. Noteworthy, a putative fusion of the membranes has already been reported for N. equitans and I. hospitalis [20]. Numbers refer to predicted enzymes involved in the respective metabolic function (Supplementary Tables 1 and 2). Individual, predicted enzymatic reactions are depicted in Fig. S5