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. Author manuscript; available in PMC: 2020 Sep 27.
Published in final edited form as: ACS Sens. 2019 Aug 21;4(9):2403–2411. doi: 10.1021/acssensors.9b00994

Fig. 6.

Fig. 6

Electrochemical fouling by serotonin (5-HT) and 5-HIAA. CV of 1 μM serotonin from 1st (dashed) and 25th (solid) 3-s injection at (A) CFME and (B) ND-COOH 15/CFME. (C) Normalized peak current for repeated injections of 5-HT. The currents are significantly different by the 25th injection (****p < 0.0001, one-way ANOVA, n = 5). (D) CFME and (E) ND-COOH 15/CFME CVs of 1 μM 5-HIAA before (dashed) and after (solid) electrodes were bathed in 1 μM 5-HIAA solution with the continuous waveform application for 1 hour. (F) 1 μM 5-HIAA normalized peak current after 1 hour of 5-HIAA fouling (***p < 0.001, unpaired t-test, n = 4). All electrochemical fouling experiment were performed using the Jackson serotonin waveform in PBS pH 7.4.