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. Author manuscript; available in PMC: 2019 Oct 3.
Published in final edited form as: ChemMedChem. 2009 Aug;4(8):1354–1363. doi: 10.1002/cmdc.200900153

Table 1.

Structures of North-derived (4a–d) and South-derived (6a–d) bicyclo[3.1.0]hexene nucleosides.

Compound # Structure Base Anti-HIV activity
4a[11] graphic file with name nihms513543t1.jpg T active
4b[12] graphic file with name nihms513543t2.jpg G inactive
4c graphic file with name nihms513543t3.jpg A active
4d graphic file with name nihms513543t4.jpg C inactive
6a graphic file with name nihms513543t5.jpg T inactive
6b graphic file with name nihms513543t6.jpg G inactive
6c graphic file with name nihms513543t7.jpg A inactive
6d graphic file with name nihms513543t8.jpg C +/− active