Fig. 2.

Comparison of stress sensitivities between in vivo and in vitro bacteria. The in vivo and in vitro Burkholderia symbiont cells were exposed to a SDS, b tween 20, c protease K, d LL-37, e polymyxin B, f riptocin, g CCR0008, h CCR0179, i CCR0480, j hydrogen peroxide, k sodium chloride, l glucose, and m ethanol at the indicated concentrations. The relative growth (%) was normalized by setting untreated bacterial growth to 100%. Mean ± SD (n = 3) is shown in in vitro (solid bar) and in vivo cells (open bar). Statistically significant differences between in vivo and in vitro symbiont cells were analyzed by Student’s t-test with Bonferroni correction: *P < 0.05. CFU data of the stress tests are shown in Supplementary Table S3