Table I.
Relation between expression of sLex/sLea and E-selectin ligands with patient's clinical features.
| Clinical feature | sLex/a expression (mean T/N ratio ± SEM) | P-value | E-Selectin ligands expression (mean T/N ratio ± SEM) | P-value |
|---|---|---|---|---|
| Histological type | 0.577 | >0.999 | ||
| Adenocarcinoma (N=14) | 1.710±0.165 | 1.557±0.185 | ||
| Squamous cell carcinoma (N=4) | 1.448±0.220 | 1.633±0.321 | ||
| Stage of disease | 0.335 | <0.999 | ||
| I + II (N=11) | 1.500±0.222 | 1.556±0.189 | ||
| III (N=7) | 1.748±0.176 | 1.585±0.234 | ||
| Gender | >0.999 | <0.999 | ||
| Male (N=13) | 1.670±0.182 | 1.562±0.216 | ||
| Female (N=5) | 1.604±0.171 | 1.604±0.108 | ||
| Metastatic site | 0.033a | 0.500 | ||
| Bones (N=3) | 2.353±0.307 | 1.663±0.156 | ||
| Other sites (N=7) | 1.270±0.162 | 1.173±0.292 | ||
| Age | 0.347 | 0.153 | ||
| <median age (N=9) | 1.483±0.213 | 1.190±0.195 | ||
| ≥median age (N=9) | 1.820±0.166 | 1.958±0.172 | ||
| Smoking habits | <0.999 | <0.999 | ||
| Smoker (N=11) | 1.625±0.186 | 1.715±0.215 | ||
| Non-smoker (N=7) | 1.693±0.214 | 1.351±0.210 |
a
P<0.05. sLex/a; sialyl Lewis x/a; T/N, tumour/normal tissue.