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Images in 75-year-old man with advanced non–small cell lung cancer with 90% programmed death-ligand 1 (PD-L1) expression at immunohistochemistry. (a) Baseline CT image shows lobulated mass in left upper lobe, consistent with primary lung cancer (arrow). (b) Follow-up CT image obtained after 2 months of nivolumab therapy shows marked tumor shrinkage, representing response to PD-1 blockade in this high PD-L1–expressing tumor (arrow).
