Table 3.
The minimal inhibitory concentrations (MIC) of the synthesized compounds against pathogenic bacteria and fungi
| Compd. number | The minimum inhibitory concentration (MIC) (µg/mL) | ||||
|---|---|---|---|---|---|
| Bacterial species | Fungal strain | ||||
| Gram-positive bacterial strain | Gram-negative bacterial strain | ||||
| Bacillus subtilis (ATCC 6633) | Staphylococcus aureus (ATCC 29,213) | Escherichia coli (ATCC 25,922) | Pseudomonas aeruginosa (ATCC 27,853) | Aspergillus niger (RCMB 002568) | |
| 2b | 7.81 | 125.00 | 0.00 | 15.62 | 0.00 |
| 2bN | 5.02 | 62.50 | 31.25 | 7.81 | 166.6 |
| 2c | 125.00 | 250.00 | 31.25 | 62.50 | 0.00 |
| 2cN | 62.50 | 142.85 | 27.77 | 31.15 | 142.85 |
| 2fN | 166.6 | 15.62 | 1.95 | 0.97 | 7.81 |
| 2g | 31.25 | 15.62 | 0.00 | 125.00 | 0.00 |
| 2gN | 7.81 | 3.90 | 15.62 | 62.50 | 83.33 |
| 2h | 3.90 | 62.50 | 15.62 | 31.25 | 125.00 |
| 2hN | 3.90 | 31.25 | 7.81 | 15.62 | 18.51 |
| 2i | 250.00 | 31.25 | 3.90 | 1.95 | 0.00 |
| Tetracycline (standard) | 31.30 | 62.50 | 15.60 | 62.50 | - |
| Amphotericin B (standard) | - | - | - | - | 62.50 |
Notes: (-) indicates not tested. Tetracycline and Amphotericin B were used as standards against the tested bacteria and fungi, respectively.