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| Cell lines | Control shRNA | RPL22L1 shRNA | Control vector | RPL22L1-HA |
|---|---|---|---|---|
| HCT116(n = 3) | 2.84±0.99 | 1.28±0.33 | ||
| HT29(n = 3) | 22.94±3.87 | 9.44±2.67 | ||
| SW620(n = 2) | 20.45±5.45 | 12.9±2.9 | ||
| ModeK(n = 3) | 1.03±0.24 | 3.06±0.92 | ||
| SW480(n = 3) | 1.34±0.36 | 2.89±0.36 |
IC50 values (μM) ± SEM of 5-FU calculated from results of 2–3 independent experiments in Fig 5B–5F.
