Table 2. List of metabolites significantly changed in common between patients with PCG and any other kind of patients (with CC/ARC/POAG).
| Biochemicals | Super Pathway | Ratio (PCG/POAG) | Ratio (PCG/CC) | *Adjust p value(PCG versus CC versus ARC) | Ratio (PCG/ARC) | *Adjust p value(PCG/POAG) |
|---|---|---|---|---|---|---|
| glycine 2 | Amino Acid | 3.86 | 8.39 | 0.0019 | 8.99 | 0.0018 |
| phenylalanine 1 | Amino Acid | 0.91 | 1.84 | 0.0007 | 1.53 | 0.0016 |
| urea | Amino Acid | 0.94 | 0.65 | 0.0000 | 0.82 | 0.0263 |
*Regression models were used to adjust for age and gender in comparisons among three groups (PCG versus CC versus ARC), and between groups of PCG and POAG. PCG: primary congenital glaucoma; CC: congenital cataract; ARC: aged-related cataract; POAG: primary open angle glaucoma.