Fig. 2.

Functional clustering of maternal protein changes in hypothalamic preoptic areas. The altered and successfully identified 18 different proteins were analyzed. The major established functions of the 18 proteins were derived from the UniProt (http://www.UniProt.org/) and Gene Ontology (http://geneontology.org/) databases. The altered proteins participate in glucose and energy metabolism (n = 6), neuron development (n = 3), response to oxidative stress and apoptosis (n = 3), protein degradation (n = 2), synaptic transmission (n = 2), ion transport (n = 1) and transcription regulation (n = 1)