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. 2019 Oct 3;10(10):754. doi: 10.1038/s41419-019-1985-3

Fig. 8. Phlpp1-deleption promoted aggrecan deposition 8 months after injury.

Fig. 8

a) Representative images of immunohistochemistry staining for aggrecan 2 and 8 months after needle puncture. b) Quantification of aggrecan-positive area. Aggrecan-positive area decreased significantly both in WT and Phlpp1 KO mice 2 months (n = 4 per group) after injury. By 8 months (n = 5 per group), the NP showed similar percentage of positive area between control and injured Phlpp1 KO mice, but it was still decreased significantly in WT mice after injury. Two-way ANOVAs were used to assess the effect of injury and genotype