Table 3.
Metabolism related Biological Processes influenced by miRNAs differentially expressed in pituitary oncocytomas
| Term | Gene count | Genes | Fold enrichment | p value |
|---|---|---|---|---|
| GO:0006664~glycolipid metabolic process | 5 | GAL3ST3, PIGY, PIGH, ST8SIA5, CLN6 | 13.1763967 | 0.0005202 |
| GO:1903509~lipopolysaccharide metabolic process | 5 | GAL3ST3, PIGY, PIGH, ST8SIA5, CLN6 | 12.8497092 | 0.00057189 |
| GO:0009247~glycolipid biosynthetic process | 4 | GAL3ST3, PIGY, PIGH, ST8SIA5 | 18.564953 | 0.00123325 |
| GO:0006643~membrane lipid metabolic process | 5 | GAL3ST3, PIGY, PIGH, ST8SIA5, CLN6 | 7.62164125 | 0.00389079 |
| GO:0046467~membrane lipid biosynthetic process | 4 | GAL3ST3, PIGY, PIGH, ST8SIA5 | 9.01341922 | 0.00942844 |
| GO:0044262~cellular carbohydrate metabolic process | 5 | GAL3ST3, CLK2, INPP5E, PPP1CC, CALM1 | 5.73732404 | 0.01045816 |
| GO:0044255~cellular lipid metabolic process | 9 | GAL3ST3, PTK2, PIGY, PIGH, PRKAB2, ST8SIA5, INPP5E, CRAT, CLN6 | 2.68328539 | 0.01584233 |
| GO:0044264~cellular polysaccharide metabolic process | 3 | GAL3ST3, PPP1CC, CALM1 | 9.51927438 | 0.03831898 |
| GO:0008610~lipid biosynthetic process | 6 | GAL3ST3, PIGY, PIGH, PRKAB2, ST8SIA5, INPP5E | 2.99002849 | 0.046311 |
| GO:0005976~polysaccharide metabolic process | 3 | GAL3ST3, PPP1CC, CALM1 | 8.04214559 | 0.05189019 |
| GO:0044723~single-organism carbohydrate metabolic process | 6 | GAL3ST3, CLK2, ST8SIA5, INPP5E, PPP1CC, CALM1 | 2.84417344 | 0.05523079 |
| GO:0006629~lipid metabolic process | 9 | GAL3ST3, PTK2, PIGY, PIGH, PRKAB2, ST8SIA5, INPP5E, CRAT, CLN6 | 2.10426065 | 0.05563828 |
| GO:0019538~protein metabolic process | 24 | BCKDK, PIGY, L3MBTL2, PRKAB2, PKN2, NDFIP1, HMG20A, UBE2C, KAT5, PPP1CC, CAMK2N1, CCNB1, URM1, PTK2, POLE4, HIF1AN, CLK2, PIGH, ST8SIA5, USP35, FBXL14, GFRA2, CALM1, CLN6 | 1.36762161 | 0.0628948 |
| GO:1901137~carbohydrate derivative biosynthetic process | 6 | GAL3ST3, PIGY, PIGH, DTYMK, ST8SIA5, CALM1 | 2.46796002 | 0.08915693 |
| GO:0010563~negative regulation of phosphorus metabolic process | 5 | CCNB1, UBE2C, CAMK2N1, GFRA2, CALM1 | 2.85811547 | 0.09220633 |
| GO:0045936~negative regulation of phosphate metabolic process | 5 | CCNB1, UBE2C, CAMK2N1, GFRA2, CALM1 | 2.85811547 | 0.09220633 |
| GO:0006796~phosphate-containing compound metabolic process | 15 | BCKDK, PIGY, PRKAB2, DTYMK, PKN2, UBE2C, PPP1CC, CAMK2N1, CCNB1, PTK2, CLK2, PIGH, INPP5E, GFRA2, CALM1 | 1.51295636 | 0.09396383 |
| GO:0006793~phosphorus metabolic process | 15 | BCKDK, PIGY, PRKAB2, DTYMK, PKN2, UBE2C, PPP1CC, CAMK2N1, CCNB1, PTK2, CLK2, PIGH, INPP5E, GFRA2, CALM1 | 1.51001763 | 0.09515533 |
| GO:0005975~carbohydrate metabolic process | 6 | GAL3ST3, CLK2, ST8SIA5, INPP5E, PPP1CC, CALM1 | 2.39817195 | 0.09782965 |