Table 2.
Selection of commercially available magnetic beads for biotechnological purification and medical applications.
Product | Size (μm) | Surface groups | Materials | Application | Manufacturer |
---|---|---|---|---|---|
Dynabeads | 1-4.4 | Carboxyl, streptavidin, antibodies, antigens, DNA/RNA | ION + PS shell | Purification, analysis | Invitrogen |
SiMAG | 0.5-1 | OH, COOH, SO3H, PO3H2, NH2, DEAE, PEI, C1, C2, C8, C18, Protein A, streptavidin, heparin | ION + SiOx | Purification, analysis | Chemicell GmbH |
SPHERO | 1-120 | Amino, carboxyl, diethylamino, dimethylamino, hydroxyethyl | ION + PS shell | Purification, analysis | Spherotech, inc. |
Pure proteome | 0.3-10 | Carboxyl, streptavidin, protein, N-hydroxy-succinimide (NHS) | ION + Polymer | Purification, sorting | Emd millipore |
Pierce beads | 1-10 | Streptavidin, protein, NHS, antibodies, glutathione | ION + polymer | Purification, analysis | Thermo scientific |
Sera-mag | 1 | Carboxyl, streptavidin, neutravidin, oligo amine, protein | ION + PS shell | Purification | GE lifescience |
Biomag | 1.5 | Carboxyl, streptavidin, amine, antigen, antibody | ION + SiOx | Purification, medical | Polysciences, inc. |
GenoPrep | Hydroxyl | ION + SiOx | Purification | GenoVision | |
MagaZorb | 1-10 | Hydroxyl | ION + Cellulose | Purification | Cortex biochem |
MagneSil | 5-8.5 | Hydroxyl | ION + SiOx | Purification | Promega |
MagPrep | 1 | Hydroxyl | ION + SiOx | Purification | Merck |
MagSi | 1-5 | Hydroxyl | Purification | MagneMedics | |
MGP | Hydroxyl | ION + Pore free glass shell | Purification | Roche Diagnostics | |
M-PVA | 0.5-8 | PVA | ION + PVA | Purification | Chemagen |
Sicastar | 1-6 | Maleic acid, Protein A + G, Carboxyl, Streptavidin, IDA/NTA | ION + PS-maleic acid copolymer | Purification | Micromod |
BcMag | 1, 5 | Hydroxyl | ION + SiOx | Purification | Bioclone |
BioMag | 1 | Hydroxyl | ION + SiOx | Purification | Bangs Lab |
μMACS | 0.05 | Hydroxyl | ION + Dextran | Purification | Miltenyi |
MPG | 5 | Hydroxyl | ION + Boro-silicate glass | Purification | PureBiotech |
Nucleo-Adembeads | 0.1-0.5 | Hydroxyl | ION + Polymer | Purification | Ademtech |
Scigen M | 3.5 | Hydroxyl | ION + Cellulose | Purification | Vector Lab |
Feridex Combidex | 0.015-0.2 | Hydroxyl | ION + Dextran | Medical | Guerbet |
Resovist Supravist | 0.02, 0.06 | Hydroxyl | ION + Carboxydextran | Medical | Schering |
Clariscan Abdoscan | 0.02, 3.5 | Hydroxyl, Sulphonated styrene | ION + PEGStarch + SO3-PS-DVB | Medical | GE-Healthcare |
VSOP-C184 | 0.007 | Carboxyl | ION + Citrate | Medical | Ferropharm |