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. 2019 Oct 3;9:14288. doi: 10.1038/s41598-019-50756-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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TLR3 mRNA expression is associated with a good prognosis in early-stage NSCLC. TLR3 expression was examined in the KM-Plotter public gene expression NSCLC datasets¹². NSCLC patients were stratified by tertiles with regard to TLR3 mRNA expression (probe ID 206271_at). Red line: high TLR3 expression; black line: low TLR3 expression. (A) OS probability of patients by TLR3 mRNA level, n = 1926. (B) OS probability of patients by TLR3 mRNA in only stage I NSCLC cases, n = 577. (C) OS probability of patients by TLR3 mRNA in only stage II NSCLC cases, n = 244. (D) OS probability of patients by TLR3 mRNA in only stage I smokers NSCLC cases, n = 267. (E) OS probability of patients by TLR3 mRNA in only stage I no smokers NSCLC cases, n = 99.