Table 1.
Demographics of study subjects
| Schizophrenia patients (n = 19) (mean ± SEM) | Controls (n = 20) | p-value | |
|---|---|---|---|
| Age (years) | 35.1 ± 2.1 | 36.85 ± 2.7 | 0.61 |
| Gender (male/female) | 19/0 | 18/2 | 0.256 |
| Injected radioactivity (MBq) | 198.6 ± 9.1 | 198.5 ± 9.7 | 0.9 |
| Injected mass per body weight (µgm/kg) | 0.023 ± 0.003 | 0.024 ± 0.003 | 0.6 |
| BMI (kg/m2) | 29.3 ± 1 | 25.2 ± 0.8 | 0.003* |
| Mean age at onset (years) | 23.05 ± 1.2 | n/a | n/a |
| Mean duration of illness (years) | 11.3 ± 2.2 | n/a | n/a |
| PANSS | n/a | n/a | |
| Positive | 14.5 ± 0.4 | ||
| Negative | 21.4 ± 1 | ||
| General | 26.5 ± 0.8 | ||
| Total | 62.5 ± 1.9 | ||
| SANS-25 | 55.7 ± 5 | n/a | n/a |
| Revised social anhedonia scale | 17.6 ± 1.9 | 9.8 ± 1.7 | 0.004* |
| Revised physical anhedonia scale | 23.3 ± 2.8 | 13.3 ± 3 | 0.017* |
| Temporal experience pleasure scale | |||
| Anticipatory pleasure scale | 38.9 ± 2.6 | 43.2 ± 2 | 0.2 |
| Consummatory pleasure scale | 28.3 ± 2.3 | 35 ± 1.7 | 0.025* |
| Genotyping rs1799971- | |||
| A:A | 16 | 15 | 0.9 |
| G:A | 3 | 4 | |
| G:G | 0 | 1 | |
| Calgary depression scale total score | 7.7 ± 1.5 | n/a | n/a |
| Number of cigarette smoked per day | 8.2 ± 2.1 | 0.9 ± 0.6 | 0.001* |
There were no significant differences in demographics other than for body mass index (BMI) and number of cigarettes smoked per day
n/a not applicable; *p < 0.05