Table 1.
SCFA production by P gingivalis, F alocis, and F nucleatum species is highly variable
| SCFA (mmol/L ) | P gingivalis 33277 | F alocis 35896 | F nucleatum 25586 | |||
|---|---|---|---|---|---|---|
| Control | CSE | Control | CSE | Control | CSE | |
| Propionate | 0.85 (0.20) | 1.22 (0.12)* | 6.95 (9.26) | 20.13 (10.62)# | 2.06 (1.46) | 1.24 (0.39) |
| Isobutyrate | 0.58 (0.20)**/## | 0.46 (0.08)***/### | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) |
| Butyrate | 4.67 (1.03)**/# | 6.02 (0.90)**/# | 15.83 (0.70) | 15.83 (0.42) | 13.19 (4.41) | 12.76 (3.23) |
| Isovalerate | 1.34 (0.20)***/### | 1.48 (0.14)***/### | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) |
Oral bacteria were grown with or without cigarette smoke extract (CSE; 2000 ng/ml nicotine equivalents). SCFA release by cultures in late log or early stationary phase was monitored using GC/MS (normalized to cell number). Interspecies differences in SCFA release between control or CSE‐treated cultures were determined by ANOVA. Intraspecies differences in SCFA release from control vs CSE‐exposed cultures were determined by t test. Values are presented as mean ± standard deviation.
P < 0.05 (#/*); 0.01 (##/**) or 0.001 (###/***), respectively, compared to *F alocis or # F nucleatum.