Table 2.

Main effect of Group on frontostriatal resting-state functional connectivity

Seed1	Target(s)2	MNI (x,y,z)	SPM t-threshold	Cluster size mm3	Control 3	Opioid 3	F(1,56)4	p-value	d 5
L.NAcc	L.vmPFC	−12 32 −12	pvoxel <.001, pcluster < .05 FWE	870.75	.14 (.03)	.01 (.03)	8.69	0.005	0.76
R.NAcc	none

Note. Standard error reported in parentheses next to mean where applicable.

¹Nucleus Accumbens

²Ventromedial Prefrontal Cortex

³group mean (SE) cluster rZ value

⁴covariates included: age, education, image quality rating (IQR)

⁵cohen’s d calculated based on Control and Opioid group marginal means