Table 1:
Characteristics of included Sleeve Gastrectomy and Intragastric Balloon Studies
| Study (Year ) | Study Type |
Interventions | Sample size |
Age, years |
Sex, female (%) |
BMI, kg/m2 (meant± s.d.) |
Pre- T1/2, min (mean ±s.d.) |
Time of 2nd |
Post- T1/2, min (mean ± s.d.) |
Length | Type of Test | Type of Meal |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Melissas (2007) | Single arm | LSG | 11 | 41.5±10.7 | 72.7% | 48±5.9 | 94.3 ± 15.4 | 6 months | 47.6 ± 23.2 | 1.5 | Scintigraphy | Solid 390 calories (52% fat, 32% protein, 16% CHO) |
| Bernstine (2009) | Single arm | LSG | 21 | 35(Range 19-58) | 85.7% | 45 | 62.4 ± 19.8 | 3 months | 56.8±18.7 | 4 | Scintigraphy | Solid 230 kcal (35% fat, 18% protein 47% CHO |
| Michalsky (2013) | Single arm | LSG | 4 | N/A | N/A | N/A | 57.5±12.7 | 3 months | 32.3±17.3 | 1.5 | Scintigraphy | Solid Unknown kcal ( 2 slices of bread, 2 eggs, 250 ml black tea) |
| Pilone (2013) | Single arm | LSG | 45 | N/A | N/A | N/A | 80.4±33.1 | 3 months | 64.3±40 | 4 | Scintigraphy | Semi-solid 230 kcal (35% fat 18% protein 47% CHO) |
| Melissas (2013) | Single arm | LSG | 21 | 38 | N/A | 46.8 (Range 35.8-62.5) | 63.7±16.5 | 4 months | 53.2±20.1 | 4 | Scintigraphy | Solid 358 kcal (50% fat, 20% protein, 30% CHO) |
| Kandeel (2015) | Single arm | LSG | 45 | 32.5±8.1 | 80% | 49.1±7.1 | 74.9±7.1 | 1 month | 28.4±8.3 | 2 | Scintigraphy | Solid 2 meals, pre 2 egg sandwich, post LSG 1 egg |
| Vigneshwaran (2016) | Single arm | LSG | 20 | 41.6±9.5 | 45% | 33.4±1.2 | 38.4±13 | 3 - 6 months | 20.3±7.6 | N/A | Scintigraphy | Semi-solid Unknown Kcal. Grounded rice |
| Vives (2017) 3cma | RCT | LSG | 30 | 51.3±12.1 | 73.3% | 51±5.2 | 96.5±78.9 | 6 months | 44.3±21.1 | 1 | Scintigraphy | Semi-solid 400 kcal ( 30% fat, 15% protein 55% CHO) |
| Vives (2017) 8cma | RCT | LSG | 30 | 50.5±10.6 | 70% | 51.3±7.2 | 99.9±71.4 | 6 months | 48.1±21.6 | 1 | Scintigraphy | Same as above |
| Sista (2017) | Single arm | LSG | 26 | 40.9±12.5 | 69.2% | 46.7±4.2 | 68.7±25 | 3 months | 33.5±18 | 2 | Scintigraphy | Solid 80-82 calorie boiled egg |
| Barkin (1988) | Single arm | IGB- Air | 26 | 37 | 58% | 100±25 | 0.5 month | 90 ± 10 | 2.5 | Scintigraphy | Solid 2 eggs. 2 pieces of white toast, followed by 300 ml of clear juice. | |
| Velchik(1989) | Single arm | IGB- Air | 10 | 36 | 100% | 57± 27.8 | 1 month | 67 ± 27.8 | 2 | Scintigraphy | Solid 300 kcal egg white sandwich (20% fat) | |
| Mion (2005) | Single arm | IGB- Fluid | 15 | 34.9 | 86% | 34.4 ±0.7 | 92±45 | 1 month | 157 ± 70 | 4 | Breath | Solid 250 kcal 1 egg 2 slices bread 5g margarine [13C]-octanoic acid |
| Su (2013) | Single arm | IGB-Fluid | 3 | 36.8±9.2 | 66.7% | 40.9±15.2 | 114±18.5 | 3 months | 375.3 ± 207 | 2 | Scintigraphy | Solid 260 kcal egg white sandwich |
| Gomez (2016) | RCT | IGB-Fluid/Placebt | 13 | 38.1±8.8 | 87% | 34.7±3.4 | 64.7±39.79 | 4 months | 212.4±167.6 | 2 | Scintigraphy | Solid 255 kcal egg white sandwich with jam and 120 ml of water |