Figure 4.

Intranasal administration of rat rOPN attenuated cell apoptosis in the brain at 24 h after SAH. rOPN administration significantly decreased the amount of TUNEL‐positive cells and attenuated cell apoptosis in the brain at 24 h after SAH. Sample size is 9, n = 3 per group. Data were presented as mean ± SD, mean ± SD is 77 ± 14.11 in Sham group, 438.7 ± 42.34 in SAH + Vehicle group, 263 ± 38.04 in SAH + rOPN group; F = 85.62. Scale bar = 50 µm. The red box on brain slice image indicates the locations observed. * P < .05 vs Sham group; #P < .05, vs SAH + Vehicle group