Figure 1.

Experimental design and animal groups. C/EBPβ, CCAAT/enhancer binding protein beta; CRISPR, clustered regularly interspaced short palindromic repeats; DMSO, dimethyl sulfoxide; GFAP, glial fibrillary acidic protein; GMH, germinal matrix hemorrhage; IF, immunofluorescence; IL‐17RA, interleukin‐17 receptor; PCNA, proliferating cell nuclear antigen; Sec, secukinumab; WB, Western blot. ^*Extra 2 pups were used for IF (IL‐17RA and GFAP) at 72 h after GMH. ^**Extra 2 pups were used for IF (Ki67, PCNA and GFAP) at the 72 h after GMH