Table 1. Clinicopathological features of 182 patients after radical operation for carcinoma of stomach in gastric cancer.
Parameters | Number (%) | Low-SII <600×109 cells/L (%) | High-SII ≥600×109 cells/L (%) | χ2 | P value |
---|---|---|---|---|---|
Cases (n) | 113 | 69 | |||
Age (years) | 0.196 | 0.657 | |||
<60 | 115 (63.2) | 70 (61.9) | 45 (65.2) | ||
≥60 | 67 (36.8) | 43 (38.1) | 24 (34.8) | ||
Gender | 0.697 | 0.404 | |||
Male | 133 (73.1) | 85 (75.2) | 48 (69.6) | ||
Female | 49 (26.9) | 28 (24.8) | 21 (30.4) | ||
Postoperative chemotherapy | 0.472 | 0.492 | |||
Yes | 137 (75.3) | 87 (77.0) | 50 (72.5) | ||
No | 45 (24.7) | 26 (23.0) | 19 (27.5) | ||
Radical resection | 2.288 | 0.319 | |||
R0 | 136 (74.7) | 87 (77.0) | 49 (71.0) | ||
R1 | 23 (12.6) | 11 (9.7) | 12 (17.4) | ||
R2 | 23 (12.6) | 15 (13.3) | 8 (11.6) | ||
Type of surgery | 3.119 | 0.210* | |||
Distal gastrectomy | 107 (58.8) | 70 (61.9) | 37 (53.6) | ||
Proximal gastrectomy | 12 (6.6) | 9 (8.0) | 3 (4.3) | ||
Total gastrectomy | 63 (34.6) | 34 (30.1) | 29 (42.0) | ||
Differentiation | 0.116 | 0.944* | |||
Poorly differentiated | 111 (61.0) | 70 (61.9) | 41 (59.4) | ||
Moderately differentiated | 66 (36.3) | 40 (35.4) | 26 (37.7) | ||
Well differentiated | 5 (2.7) | 3 (2.7) | 2 (2.9) | ||
Primary tumor site | 6.111 | 0.047 | |||
Upper 1/3 | 16 (8.8) | 11 (9.7) | 5 (7.2) | ||
Middle 1/3 | 74 (40.7) | 38 (33.6) | 36 (52.2) | ||
Low 1/3 | 92 (50.5) | 64 (56.6) | 28 (40.6) | ||
Pathology | 3.739 | 0.442* | |||
Adenocarcinoma | 122 (67.0) | 78 (69.0) | 44 (63.8) | ||
Mucinous carcinoma | 19 (10.4) | 8 (7.1) | 11 (15.9) | ||
Signet ring cell carcinoma | 28 (15.4) | 18 (15.9) | 10 (14.5) | ||
Mixed carcinoma | 13 (7.1) | 9 (8.0) | 4 (5.8) | ||
TNM stage | 6.053 | 0.442 | |||
IIIA | 73 (40.1) | 50 (44.2) | 23 (33.3) | ||
IIIB | 75 (41.2) | 48 (42.5) | 27 (39.1) | ||
IIIC | 34 (18.7) | 15 (13.3) | 19 (27.5) | ||
Total lymph nodes | 3.080 | 0.079 | |||
<23 | 89 (48.9) | 61 (54.0) | 28 (40.6) | ||
≥23 | 93 (51.1) | 52 (46.0) | 41 (59.4) | ||
Positive lymph nodes | 1.217 | 0.270 | |||
<7 | 86 (47.3) | 57 (50.4) | 29 (42.0) | ||
≥7 | 96 (52.7) | 56 (49.6) | 40 (58.0) | ||
MLNR | 1.283 | 0.257 | |||
<0.33 | 34 (18.7) | 24 (21.2) | 10 (14.5) | ||
≥0.33 | 148 (81.3) | 89 (78.8) | 59 (85.5) | ||
CEA (ng/mL) | 0.023 | 0.879 | |||
<2.46 | 91 (50.0) | 57 (50.4) | 34 (49.3) | ||
≥2.46 | 91 (50.0) | 56 (49.6) | 35 (50.7) | ||
CA199 (U/mL) | 2.824 | 0.092 | |||
<12.33 | 91 (50.0) | 62 (54.9) | 29 (42.0) | ||
≥12.33 | 91 (50.0) | 51 (45.1) | 40 (58.0) | ||
Lauren classification | 0.326 | 0.849 | |||
Intestinal | 118 (64.8) | 75 (66.4) | 43 (62.3) | ||
Diffuse | 24 (13.2) | 14 (12.4) | 10 (14.5) | ||
Mixed | 40 (22.0) | 24 (21.2) | 16 (23.2) | ||
Borrmann classification | 2.510 | 0.643* | |||
Borrmann I | 4 (2.2) | 4 (3.5) | 0 (0.0) | ||
Borrmann II | 26 (14.3) | 16 (14.2) | 10 (14.5) | ||
Borrmann III | 123 (67.6) | 75 (66.4) | 48 (69.6) | ||
Borrmann IV | 29 (15.9) | 18 (15.9) | 11 (15.9) | ||
Tumor size (mm) | 1.711 | 0.191 | |||
<50 | 58 (31.9) | 40 (35.4) | 18 (26.1) | ||
≥50 | 124 (68.1) | 73 (64.6) | 51 (73.9) |
*, Fisher exact test.