Table 3. Correlation between KRAS mutational status and clinical characteristics.
| Variable | KRAS, n (%) | Total, n (%) | P value | |
|---|---|---|---|---|
| Mutant (n=140) | Wild (n=220) | |||
| Sex | 0.027 | |||
| Male | 78 (55.7) | 158 (71.8) | 236 (65.6) | |
| Female | 62 (44.3) | 62 (28.2) | 124 (34.4) | |
| Age at diagnosis (years) | <0.001 | |||
| <40 | 12 (8.6) | 58 (26.4) | 70 (19.4) | |
| 40–60 | 66 (47.1) | 132 (60.0) | 198 (55.0) | |
| >60 | 62 (44.3) | 30 (13.6) | 92 (25.6) | |
| Initial complaint | 0.002 | |||
| Perforation | 36 (25.7) | 34 (15.5) | 70 (19.4) | |
| Obstruction | 54 (38.6) | 56 (25.5) | 110 (30.6) | |
| Constipation | 32 (22.9) | 58 (26.4) | 90 (25.0) | |
| Bleeding | 0 (0.0) | 36 (16.4) | 36 (10.0) | |
| Others | 18 (12.9) | 36 (16.4) | 54 (15.0) | |
| Site of disease | <0.001 | |||
| Rt. side | 18 (12.9) | 36 (16.4) | 54 (15.0) | |
| Transverse | 30 (21.4) | 22 (10.0) | 52 (14.4) | |
| Lt. side | 48 (34.3) | 42 (19.1) | 90 (25.0) | |
| Sigmoid | 10 (7.1) | 80 (36.4) | 90 (25.0) | |
| Rectal | 34 (24.3) | 40 (18.2) | 74 (20.6) | |
| No. of mets | <0.001 | |||
| Single | 0 (0.0) | 36 (16.4) | 36 (10.0) | |
| Multiple | 140 (100.0) | 184 (83.6) | 324 (90.0) | |
| Site of mets | <0.001 | |||
| Liver | 18 (12.9) | 144 (65.5) | 162 (45.0) | |
| Lung | 34 (24.3) | 38 (17.3) | 72 (20.0) | |
| Liver + lung | 88 (62.9) | 20 (9.1) | 108 (30.0) | |
| Others | 0 (0.0) | 18 (8.2) | 18 (5.0) | |
Rt., right; Lt., left; mets, metastasis.