A model comparing the gene network of KNAT7 in Arabidopsis and rice. A, Regulatory network of Arabidopsis KNAT7. NAC SECONDARY WALL THICKENING PROMOTING3 (AtNST3)/SECONDARY WALL-ASSOCIATED NAC DOMAIN1 (AtSND1), AtMYB46, and AtMYB61 directly bind to the promoter of AtKNAT7. AtKNAT7 physically interacts with OVATE FAMILY PROTEIN4 (AtOFP4), BELL1-LIKE HOMEODOMAIN6 (AtBLH6), and AtMYB75. AtKNAT7 and its interacting partners act as transcriptional suppressors of downstream secondary cell wall gene expression. B, Regulatory network of rice KNAT7. OsKNAT7 physically interacts with OsNAC31, GROWTH-REGULATING FACTOR4 (OsGRF4), and OsOFP2. OsKNAT7 suppresses the function of OsNAC31 in activating OsMYB61, which further activates the expression of cellulose synthase CESA. Similarly, OsKNAT7 suppresses the function of OsGFP4 in activating EXPANSIN (EXP) expression. OsOFP2 is a negative regulator of GA signaling. → denotes promoter binding and activation. –| denotes physical interaction and suppression. ---| denotes indirect suppression.