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. 2019 Oct 3;17:102. doi: 10.1186/s12951-019-0536-5

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Cellular adhesion behavior on various substrates. a Upper, immunofluorescence observation of cellular cytoskeletonal morphology by staining the actin (red), and nuclei (blue). Middle, SEM observation of the typical cellular pseudopodia. Lower, the corresponding local amplification of filopodia (white arrows). b The corresponding quantitative analysis of cellular Feret’s dimeter, average cell area, circularity and aspect ratio. c Cellular viability analysis (CCK-8 assay) for cellular adhesion (6 and 24 h) and proliferation (2 and 5 days)