Figure 2.
Young plasma diminishes pro-inflammatory and senescence phenotypes in old adipose tissue in heterochronic parabiosis system. Mouse (C57/Bl6: male) adipose tissue samples were collected from either isochronic young (Y-iso) or old (O-iso), and heterochronic young (Y-het) or old (O-het) groups following 4 weeks of parabiosis. (A) Levels of MCP-1 and (B) IL-6 in the adipose tissue lysate as quantified by ELISA. Statistical significance was determined by paired t test (n = 6 for each group) and expressed as * p < .05 or **p < .001.