Table III.
ISR/ISO and no ISR/ISO analysis
| Parameter | BMS | DES | ||||
|---|---|---|---|---|---|---|
| ISR/ISO (n = 54) | No ISR/ISO (n = 220) | P-value | ISR/ISO (n = 31) | No ISR/ISO (n = 105) | P-value | |
| Age [years] | 65 ±8 | 68.2 ±8.7 | 0.012 | 63.4 ±8.5 | 67.1 ±8.4 | 0.013 |
| Men, n (%) | 36 (8.8) | 161 (39.3) | 0.340 | 23 (5.6) | 71 (17.3) | 0.486 |
| Women, n (%) | 18 (4.4) | 59 (14.4) | 8 (1.9) | 34 (8.3) | ||
| Time to detection of ISR/ISO, mean ± SD [month] | 20.5 ±21.3 | n/a | n/a | 15.8 ±12 | n/a | 0.228 |
| C-reactive protein, mean ± SD [mg/l] | 4.14 ±4.2 | 3.74 ±6.59 | 0.103 | 4.43 ±3.07 | 2.9 ±3.41 | 0.334 |
| Low-density lipoprotein, mean ± SD [mmol/l] | 2.47 ±0.83 | 2.58 ±0.82 | 0.298 | 2.61 ±1.03 | 2.49 ±0.76 | 0.120 |
| Creatinine, mean ± SD [μmol/l] | 89.7 ±19.5 | 93 ±35.6 | 0.45 | 90 ±24.4 | 88.6 ±23.1 | 0.94 |
| Glucose, mean ± SD [mmol/l] | 6.03 ±1.36 | 6.04 ±1.57 | 0.088 | 5.44 ±0.83 | 6.19 ±2.1 | 0.59 |
| Diabetes mellitus, n (%) | 17 (31.5) | 52 (23.6) | 0.234 | 6 (19.4) | 36 (34.3) | 0.114 |
| Hypertension, n (%) | 54 (100) | 208 (94.5) | 0.265 | 30 (96.8) | 97 (92.4) | 0.387 |
| Left vertebral artery, n (%) | 32* (7.8) | 127 (31.1) | 0.725 | 16 (3.9) | 50 (12.2) | 0.696 |
| Right vertebral artery, n (%) | 22* (5.1) | 93 (22.7) | 15 (3.7) | 55 (13.4) | ||
| Stent diameter, mean ± SD [mm] | 4.22 ±0.78 | 4.23 ±0.76 | 0.32 | 3.41 ±0.49 | 3.40 ±0.54 | 0.23 |
| Stent length, mean ± SD [mm] | 11.8 ±2.1 | 11.9 ±2.8 | 0.72 | 13.5 ±3.1 | 11.6 ±4.1 | 0.024 |
| Biolimus, n | n/a | n/a | n/a | 4 | 27 | 0.159 0.063# |
| Everolimus, n | n/a | n/a | n/a | 11 | 41 | |
| Zotarolimus, n | n/a | n/a | n/a | 10 | 24 | |
| Paclitaxel, n | n/a | n/a | n/a | 3 | 2 | |
| Sirolimus, n | n/a | n/a | n/a | 3 | 11 | |
| Stainless steel, n | 24 | 111 | 0.103 0.034** |
n/a | n/a | n/a |
| Cobalt-chromium, n | 23 | 98 | n/a | n/a | n/a | |
| Platinum-chromium, n | 7 | 11 | n/a | n/a | n/a | |
*
One patient with left and right vertebral artery ISR/ISO
**
p-value for stainless steel and cobalt-chromium vs platinum-chromium BMS.
#
P-value for paclitaxel and zotarolimus vs. other types of DES.