Table 2. Baseline Characteristics of All Individuals From the Copenhagen General Population Study and of Those Eligible for Statin Therapy According to 5 Major Statin Guidelines for Primary Prevention of Atherosclerotic Cardiovascular Disease.
| Characteristics | All Individuals | Statin Eligibility According to Guidelines | ||||
|---|---|---|---|---|---|---|
| CCS | ACC/AHA | NICE | USPSTF | ESC/EAS | ||
| Individuals, No. | 45 750 | 19 953 | 19 400 | 18 196 | 13 966 | 6870 |
| Male, No. (%) | 19 870 (43) | 11 431 (57) | 11 785 (61) | 9947 (55) | 9200 (66) | 2547 (37) |
| Age, median (IQR), y | 56 (48-64) | 62 (56-68) | 64 (58-70) | 65 (60-70) | 66 (61-70) | 63 (58-68) |
| Blood pressure, median (IQR), mm Hg | ||||||
| Systolic | 139 (125-152) | 150 (135-163) | 148 (135-162) | 148 (135-162) | 152 (140-166) | 148 (133-164) |
| Diastolic | 84 (77-90) | 88 (80-95) | 87 (80-95) | 85 (80-94) | 88 (80-95) | 86 (80-95) |
| Plasma cholesterol, median (IQR), mg/dL | ||||||
| Total cholesterol, mg/dL | 220 (197-247) | 244 (220-267) | 236 (213-267) | 236 (209-263) | 236 (209-263) | 252 (224-286) |
| HDL cholesterol, mg/dL | 61 (49-76) | 55 (46-68) | 56 (45-71) | 56 (45-71) | 55 (43-70) | 62 (50-77) |
| LDL cholesterol, mg/dL | 128 (108-155) | 147 (131-170) | 143 (120-170) | 139 (116-162) | 143 (120-166) | 155 (128-182) |
| Current smoker, No. (%) | 9907 (21) | 5981 (30) | 6140 (32) | 5497 (30) | 4987 (36) | 1942 (28) |
| Diabetes, No. (%) | 861 (2) | 861 (4) | 795 (4) | 817 (4) | 631 (5) | 861 (13) |
| 10-y PCE risk, median (IQR), % | 5.4 (1.9-12.6) | 13.3 (7.6-20.9) | 14.2 (9.9-21.2) | 15.0 (10.5-22.0) | 17.6 (13.2-24.4) | 13.7 (6.2-21.8 |
Abbreviations: ACC, American College of Cardiology; AHA, American Heart Association; ASCVD, atherosclerotic cardiovascular disease; CCS, Canadian Cardiovascular Society; ESC, European Society of Cardiology; EAS, European Atherosclerosis Society; HDL, high-density lipoprotein; IQR, interquartile range; LDL, low-density lipoprotein; NICE, National Institute for Health and Care Excellence; PCE, pooled cohort equations; USPSTF, US Preventive Services Task Force.
SI conversion factor: To convert cholesterol levels to millimoles per liter, multiply by 0.0259.