Table 2. Risk Factors Associated With 30-Day Readmission After Cardiac Arrest–Related Index Hospitalization.
| Covariate | VT or VF | PEA or Asystole | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariatea | Multivariableb | Univariatea | Multivariableb | |||||
| Unadjusted HR (95% CI) | P Value | Adjusted HR (95% CI) | P Value | Unadjusted HR (95% CI) | P Value | Adjusted HR (95% CI) | P Value | |
| Female | 1.14 (1.07-1.21) | <.001 | 1.05 (0.99-1.12) | .13 | 1.08 (1.04-1.12) | <.001 | 1.06 (1.02-1.11) | .002 |
| Chronic kidney disease receiving hemodialysis | 2.07 (1.92-2.24) | <.001 | 1.56 (1.43-1.70) | <.001 | 1.70 (1.62-1.78) | <.001 | 1.44 (1.36-1.52) | <.001 |
| Prolonged hospital stayc | 1.71 (1.61-1.81) | <.001 | 1.38 (1.30-1.48) | <.001 | 1.46 (1.40-1.52) | <.001 | 1.35 (1.29-1.41) | <.001 |
| History of congestive heart failure | 1.58 (1.49-1.68) | <.001 | 1.27 (1.20-1.36) | <.001 | 1.42 (1.37-1.48) | <.001 | 1.19 (1.14-1.24) | <.001 |
| Chronic kidney disease | 1.53 (1.43-1.64) | <.001 | 1.21 (1.12-1.30) | <.001 | 1.35 (1.29-1.41) | <.001 | 1.17 (1.12-1.23) | <.001 |
| Chronic pulmonary disease | 1.34 (1.25-1.43) | <.001 | 1.16 (1.08-1.25) | <.001 | 1.27 (1.21-1.33) | <.001 | 1.18 (1.12-1.24) | <.001 |
| Intra-aortic balloon pump | 1.04 (0.94-1.16) | .41 | NCd | NC | 1.13 (1.00-1.27) | .048 | 1.18 (1.04-1.34) | .01 |
| Peripheral vascular disease | 1.43 (1.30-1.56) | <.001 | 1.16 (1.06-1.27) | .002 | 1.29 (1.21-1.38) | <.001 | 1.11 (1.03-1.19) | .005 |
| Percutaneous coronary intervention | 0.78 (0.73-0.83) | <.001 | 1.13 (1.03-1.24) | .007 | 0.88 (0.81-0.95) | .002 | 0.97 (0.87-1.08) | .57 |
| Diabetes | 1.35 (1.27-1.43) | <.001 | 1.08 (1.01-1.15) | .02 | 1.34 (1.29-1.40) | <.001 | 1.12 (1.07-1.17) | <.001 |
| Anemia | 1.37 (1.29-1.46) | <.001 | 1.07 (1.00-1.14) | .06 | 1.31 (1.26-1.37) | <.001 | 1.06 (1.02-1.11) | .007 |
| Urban hospital locatione | 1.14 (1.07-1.21) | <.001 | 1.08 (1.01-1.15) | .02 | 1.15 (1.10-1.20) | <.001 | 1.06 (1.01-1.10) | .009 |
| Elixhauser Comorbidity Index score >4 | 1.68 (1.58-1.79) | <.001 | 1.06 (0.97-1.15) | .24 | 1.54 (1.48-1.60) | <.001 | 1.06 (1.00-1.13) | .04 |
| Atrial fibrillation | 1.17 (1.10-1.24) | <.001 | 1.01 (0.95-1.07) | .79 | 1.13 (1.08-1.18) | <.001 | 1.05 (1.01-1.10) | .03 |
| Hypertension | 1.09 (1.03-1.16) | .003 | 0.93 (0.87-0.99) | .02 | 1.17 (1.12-1.22) | <.001 | 0.99 (0.94-1.03) | .50 |
| Coronary angiography | 0.71 (0.67-0.75) | <.001 | 0.89 (0.83-0.95) | <.001 | 0.95 (0.90-1.00) | .04 | 0.98 (0.92-1.05) | .61 |
| History of cardiac arrest | 0.72 (0.61-0.85) | <.001 | 0.81 (0.69-0.96) | .01 | 0.78 (0.67-0.92) | .003 | 0.77 (0.65-0.90) | .001 |
| Targeted temperature management | 0.66 (0.57-0.77) | <.001 | 0.76 (0.66-0.89) | <.001 | 0.90 (0.76-1.07) | .22 | NC | NC |
| Coma | 0.76 (0.65-0.89) | <.001 | 0.73 (0.62-0.84) | <.001 | 0.78 (0.70-0.86) | <.001 | 0.75 (0.67-0.82) | <.001 |
Abbreviations: HR, hazard ratio; NC, not calculated; PEA, pulseless electrical activity; VF, ventricular fibrillation or flutter; VT, ventricular tachycardia.
Univariate Cox proportional hazards regression model was created with an outcome of 30-day readmission for each covariate from Table 1.
Multivariable Cox proportional hazards regression model was created with an outcome of 30-day readmission including all covariates with P < .10 in the univariate analysis, and the covariates with P < .05 for either rhythm cohort are listed.
Length of stay days exceeding the 75th percentile (≥20 days) of the entire stay days.
Covariate with P ≥ .10 in the univariate analysis was not included in the multivariable analysis.
Rural hospital location as reference.