Table 4. Time-Related Primary and Secondary Outcome Results in a Study of the Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy.
| Time-Related Outcomes | Median (IQR)a | Difference of Medians (95% CI)b | P Value | |
|---|---|---|---|---|
| General Anesthesia (n = 183) | Procedural Sedation (n = 185) | |||
| Length of stay in ICU, h | 17.9 (2.0 to 42.4) | 0.0 (0.0 to 24.5) | 17.9 (7.4 to 22.4) | <.001 |
| Duration of mechanical ventilation, h | 3.8 (1.9 to 7.0) (n = 108) | 0.0 (0.0 to 0.0) (n = 55) | 3.8 (3.25 to 4.5) | <.001 |
| Door to groin puncture, min | 75 (60 to 91) | 69 (53 to 90) | 6 (0 to 15) | .04 |
| Computed tomography to angiography suite arrival, min | 49 (29 to 68) | 41 (28 to 62) | 8 (2 to 12) | .22 |
| Angiography suite arrival to groin puncture, min | 23 (14 to 30) | 15 (10 to 24) | 8 (5 to 11) | <.001 |
| Onset to groin puncture, min | 180 (136 to 255) | 170 (133 to 240) | 10 (−11 to 32) | .04 |
| Onset to reperfusion, min | 241.5 (200 to 348.5) | 257 (197 to 325) | −15.5 (−45 to 26.5) | .53 |
| Door to reperfusion, min | 150 (113.5 to 200) | 165 (119 to 207) | −15 (−30 to 5) | .86 |
| Groin puncture to reperfusion, min | 51.5 (31 to 90) | 70.5 (33.5 to 105) | −19 (−31 to −4) | .15 |
| Duration of intervention, min | 157.5 (82 to 232) | 160 (97 to 225) | −2.5 (−29 to 26.5) | .19 |
Abbreviations: ICU, intensive care unit; IQR, interquartile range.
a
Variables were log-transformed before calculating the P value. The same adjusted model as described above was used.
b
A nonparametric bootstrap approach was used to calculate 95% CIs.