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. 2019 Aug 29;18(5):3475–3483. doi: 10.3892/etm.2019.7960

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Inhibition of XIST suppresses bladder cancer cell proliferation or migration. 253J and RT112 cells were transfected with NC siRNA, XIST siRNA1 or XIST siRNA2. (A) qPCR was used to examine the expression of XIST. (B and C) A Cell Counting Kit-8 assay and (D and E) a wound healing assay (magnification, ×40) were used to assess the effects of the treatments on cell proliferation and migration, respectively. **P<0.01 vs. siNC. XIST, X inactive specific transcript; siRNA, small interfering RNA; siNC, negative control siRNA; siXIST, siRNA targeting XIST; OD, optical density.