Table I.
Clinical characteristics and whole-exome sequencing quality control of patients with papillary thyroid carcinoma.
| Case no. | Age, years | Sex | Multifocality | TNM stage | Tumor sequencing depth (x) | Normal sequencing depth (x) | TMB (mutations/Mb) | BRAF V600E |
|---|---|---|---|---|---|---|---|---|
| 1 | 40 | Female | Yes | T1aN0M0 | 187.32 | 99.89 | 0.29 | − |
| 2 | 29 | Female | No | T1aN0M0 | 179.27 | 98.48 | 0.35 | − |
| 3 | 43 | Female | No | T1aN0M0 | 169.37 | 86.95 | 0.38 | − |
| 4 | 65 | Male | Yes | T1aN0M0 | 82.39 | 56.64 | 0.29 | − |
| 5 | 38 | Female | Yes | T1aN1aM0 | 67.98 | 31.87 | 0.16 | − |
| 6 | 45 | Female | No | T1aN1aM0 | 159.76 | 39.63 | 1.35 | + |
| 7 | 34 | Female | No | T1aN1aM0 | 174.48 | 47.25 | 1.06 | + |
| 8 | 37 | Female | No | T1aN1aM0 | 81.04 | 46.23 | 0.32 | + |
| 9 | 29 | Female | No | T1aN1aM0 | 133.27 | 37.27 | 1.07 | + |
| 10 | 55 | Male | No | T1aN1aM0 | 150.61 | 79.92 | 0.38 | + |
TNM, Tumor-Node-Metastasis; TMB, tumor mutation burden.