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. 2019 Aug 26;18(5):3397–3404. doi: 10.3892/etm.2019.7939

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Resveratrol regulates neuronal cell apoptosis by regulating the TGF-β-mediated ERK signaling pathway. Effects of resveratrol on TGF-β and ERK (A) mRNA and (B) protein expression in neurons isolated from rats with cerebral hemorrhage. Effect of TGF-β inhibitor on the TGF-β and ERK (C) mRNA and (D) protein levels. (E) Effects of treatment with TGF-β on resveratrol-decreased ERK and pERK expression in neurons. (F) Effects of treatment with TGF-β on neuronal apoptosis. **P<0.01. TGF-β, transforming growth factor-β; ERK, extracellular signal-regulated kinase; TGF-βIR, TGF-β inhibitor; ns, not significant.