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. 2019 Sep 27;10:1124. doi: 10.3389/fphar.2019.01124

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Copyright © 2019 Tomko, O’Leary, Trask, Achenbach, Hall, Goralski, Ellis and Dupré

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of atypical cannabinoids on EGF-mediated migration and invasion. (A) Histogram summarizing Transwell migration results using MDA-MB-231 PR cells in response to EGF in presence of either the vehicle control or various concentrations of O-1602 or Abn-CBD. (B) Histogram summarizing Matrigel invasion using MDA-MB-231 PR cells in presence of either the vehicle control, O-1602, or Abn-CBD. Results represent the means ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01.