Figure 3.

Specificity of Arthrogen accumulation in joints of healthy BALB/c mice following subcutaneous injection: (A) images of dissected bones of Arthrogen-800-injected and control mIgG-800-injected mice. Auto fluorescence was scanned at 700 nm. FL = forelimb, HL = hind limb; (B) images of control organs (N = non-injected, IgG = control mIgG-800, and Arth = Arthrogen-800); (C) mean fluorescence of organs as determined from grayscale images. Contrast in 700 and 800 nm channels was adjusted to the same extent for all mice and for all organs and bones. The experiment was repeated twice.