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Downregulation of HE4 repressed cell invasion and migration of ovarian cancer cells. Transwell assays were carried out to evaluate the invasion of OVCAR3 (A) and C13K (B) cells transfected with sh-HE4 or sh-Ctrl, at 48 h, amplification, ×200. Wound healing assays were performed to determine the migration of the transfected OVCAR3 (C) and C13K (D) cells at 0 and 24 h, amplification, ×40. *P<0.05.
