Fig. 3.

TAMs infiltrating brain tumors. Twenty-four mice were inoculated with 5×10³NS/ or ML/CT-2A cells (12 mice per group). 19 days after tumor cell inoculation, mice were euthanized and the tumor-infiltrating immune cells were stained for total (A), inflammatory (B) and resident (C) TAMs infiltrating the microenvironment of NS/ and ML/CT-2A tumors (12 mice per group). The staining failed in one NS/CT-2A tumor-bearing mouse. No significant differences were found in TAMs between NS/ and ML/CT-2A tumors. Left panels, total amounts. Right panels, M2 subpopulations. NS, NS/CT-2A tumors; ML, ML/CT-2A tumors; TAMs, tumor-associated microglia/macrophages.