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. 2019 Sep 11;8(9):bio044552. doi: 10.1242/bio.044552

Fig. 5.

Fig. 5.

In vitro immune effect of CT-2A cells. Modification of MFs (A), MDSCs (B) and T cells (C) subpopulations of splenocytes after 48-h co-culture with NS/ and ML/CT-2A cells. Compared to ML/CT-2A-splenocytes co-cultures, NS/CT-2A-splenocytes co-cultures showed higher amount of MF and Tregs and significantly lower amount of gMDSCs, Total T cells, CD8+ T cells and CD4+ T cells. Values are expressed as normalized difference between the study conditions (NS/ or ML/CT-2A cells and splenocytes in NS or ML medium, respectively) and the corresponding control conditions (splenocytes in NS or ML medium, respectively). NS, NS/CT-2A cells; ML, ML/CT-2A cells; MF, macrophages; MDSCs, myeloid-derived suppressor cells; CD, cluster of differentiation; Tregs, regulatory T cells.