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. 2019 Sep 27;10:1111. doi: 10.3389/fphar.2019.01111

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Copyright © 2019 Yao, Zeng, Zhan, He, Liu, Liu, Zhang, Xiong and Xia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of OA and UA on UGT1A proteins in HepG2 cells. The effect of OA (10, 20, and 40 μM) (A) and UA (10, 20, and 40 μM) (B) on UGT1As (UGT1A1, UGT1A3, UGT1A4, and UGT1A9) protein expression in HepG2 cells was quantified by Western blotting analysis, normalized to β-actin, and compared to the control group. DMSO (0.1%) was used as negative control. RIF (10 μM) was used as the positive control. The data are expressed as the mean ± SD of triplicate independent experiments (*p < 0.05, **p < 0.01, ***p < 0.001).