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. 2019 Sep 5;3(10):1907–1916. doi: 10.1210/js.2019-00216

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Copyright © 2019 Endocrine Society

This article has been published under the terms of the Creative Commons Attribution Non-Commercial, No-Derivatives License (CC BY-NC-ND; https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure 3. — E-cigarette (ECIG) exposure misregulates receptive signaling pathways. RNA microarray on day 4.5 pseudopregnant uteri was analyzed via one-way ANOVA, and significant genes were determined with a P ≤ 0.05 and a fold change >1.14 and <0.714. (A) Hierarchal clustering of 767 significant genes, 395 upregulated and 372 downregulated. (B) Top 10 gene pathways involved in receptivity from the top 50 canonical pathways identified via Ingenuity Pathway Analysis. (C, D) CLDN10 protein expression and (E) RNA level. RNA levels were analyzed via Student t test. GE, glandular epithelium; LE, luminal epithelium; ST, stroma.