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. 2019 Sep 27;9:992. doi: 10.3389/fonc.2019.00992

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Copyright © 2019 Kalli, Voutouri, Minia, Pliaka, Fotis, Alexopoulos and Stylianopoulos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Estimation of compressive stress generated during the growth of brain cancer MCS within an agarose matrix. (A,B) Fit of the mathematical model to the experimental data of the growth of H4 (A) and A172 (B) spheroids. (C,D) The calculated by the model bulk stress generated during the growth of H4 (C) and A172 (D) spheroids.