Fig. 4.

—The apicoplast genome of Nephromyces closely resembles those of other sporozoans such as hematozoans and coccidians in terms of general organization (i.e., one single copy region and two inverted repeats that contain the rRNA-gene operons), and gene content and order. However, a shared orf59-orf88 gene cluster (surrounded by sufB and rpoB) between Nephromyces and hematozoans support their monophyly as suggested by nuclues-gene trees. Two divergent representatives are shown for the Haemosporidia, Piroplasmida, and Coccidia. Piroplasmids have slightly more divergent apicoplast genomes. Gene coloring scheme follows that in Fig. 3. Genes colored in gray represent ORFs or highly divergent genes that are otherwise syntenic with those in other apicoplast genomes.