Table 1.
Group | Description | Drug (Abbrev.) | Daily Dosage (mg) By Patient Weight | Range Of Monthly Cost (CNY) | Included In National Basic Medical Insurance List | Recommended In Standardized Treatment Regimen |
||||
---|---|---|---|---|---|---|---|---|---|---|
<50 kg | ≥50 kg | Maximum | Yes | Noc | ||||||
Most preferreda | Preferredb | |||||||||
1 | First-line oral anti-TB drugs | Pyrazinamide (Z) | 1500 | 1750 | 2000 | 58–96 | √ | √ | ||
Ethambutol (E) | 750 | 1000 | 1500 | 21–34 | √ | √ | ||||
2 | Injectable anti-TB drugs | Amikacin (Am) | 400 | 400–600 | 800 | 72–108 | √ | √ | ||
Capreomycin (Cm) | 750 | 750 | 750 | 712 | √ | √ | ||||
Kanamycin (Km) | 500 | 750 | 1000 | 1500 | √ | √ | ||||
3 | Fluoroquinolones (FQs) | Ofloxacin (Ofx) | 400 | 600 | 800 | 110–165 | √ | |||
Levofloxacin (Lfx) | 400 | 500 | 600 | 60–110 | √ | √ | ||||
Moxifloxacin (Mfx) | 400 | 400 | 400 | 698 | √ | √ | ||||
4 | Oral bacteriostatic second-line anti-TB drugs | Prothionamide (Pto) | 600 | 600–800 | 800 | 40–53 | √ | √ | ||
p-aminosalicylic acid (PAS) | 8000 | 10,000 | 12,000 | 600–900 | √ | √ | ||||
Cycloserine (Cs) | 500 | 750 | 1000 | 1620–1920 | √ | √ | ||||
5 | Anti-TB drugs with limited data on efficacy and/or long-term safety in the treatment of drug-resistant TB | Amoxicillin/Clavulanate (Amx/Clv) | 1125 | 1,500 | 1500 | 1260–1680 | √ | |||
Clarithromycin (Clr) | 500 | 750 | 1000 | 126–252 | √ | |||||
Linezolid (Lzd) | 300 | 300–600 | 600 | 9600–19,200 | √ | |||||
Clofazimine (Cfz) | 100 | 100 | 100 | 1248 | √ |