Table 2.
Do you offer predictive testing for the following variants? | Yes | No | Only to affected individuals | No response |
---|---|---|---|---|
Class 5 variant | 146 (97%) | 2 (1%) | 1 (1%) | 1 (1%) |
Class 4 variant | 123 (82%) | 2 (1%) | 23 (15%) | 2 (1%) |
Class 3 variant | 18 (12%) | 35 (23%) | 95 (63%) | 2 (1%) |
Considering predictive testing for class 4 variants | Yes | No | Defer to Cardiologist to decide | No response |
---|---|---|---|---|
Are you entirely reassuring that non-carriers have low risk of developing the family phenotype? | 22 (15%) | 101 (67%) | 21 (14%) | 6 (4%) |
Do you recommend cardiac assessment of non-carrier if one has not been performed? | 95 (63%) | 37 (25%) | 10 (7%) | 8 (5%) |
Do you recommend discontinuation of cardiac follow-up of asymptomatic individuals with negative test? | 40 (27%) | 51 (34%) | 52 (35%) | 7 (5%) |
Do you counsel patients about the possibility of reclassification of variants? | 123 (82%) | 14 (9%) | 13 (9%) | 0 |