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. 2019 Apr 12;27(8):1178–1185. doi: 10.1038/s41431-019-0391-8

Table 2.

Predictive testing for variants of class 3/4/5

Do you offer predictive testing for the following variants? Yes No Only to affected individuals No response
Class 5 variant 146 (97%) 2 (1%) 1 (1%) 1 (1%)
Class 4 variant 123 (82%) 2 (1%) 23 (15%) 2 (1%)
Class 3 variant 18 (12%) 35 (23%) 95 (63%) 2 (1%)
Considering predictive testing for class 4 variants Yes No Defer to Cardiologist to decide No response
Are you entirely reassuring that non-carriers have low risk of developing the family phenotype? 22 (15%) 101 (67%) 21 (14%) 6 (4%)
Do you recommend cardiac assessment of non-carrier if one has not been performed? 95 (63%) 37 (25%) 10 (7%) 8 (5%)
Do you recommend discontinuation of cardiac follow-up of asymptomatic individuals with negative test? 40 (27%) 51 (34%) 52 (35%) 7 (5%)
Do you counsel patients about the possibility of reclassification of variants? 123 (82%) 14 (9%) 13 (9%) 0