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. 2019 Sep 27;10:2260. doi: 10.3389/fmicb.2019.02260

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Copyright © 2019 Araos, Battaglia, Ugalde, Rojas-Herrera, Blaser and D’Agata.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential representation of taxa from the 16S rRNA amplicon sequencing. Panel (A) Volcano plot with differentially abundant features observed between subjects who acquired MDRO or not (MDRO+ or MDRO-, respectively). Only features whose relative abundances remained significantly different after correcting for multiple comparisons are labeled (FDR < 5%). A negative log2 Fold Difference in relative abundance indicates the feature predominated among MDRO-, and vice versa for MDRO+. Panels (B–D). Boxplots with the relative abundances of Odoribacter laneus, Akkermansia muciniphila and Blautia spp. among MDRO- and MDRO+ subjects. MDRO, multidrug-resistant organisms; FDR, false discovery rate.