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. 2019 Sep 27;10:2270. doi: 10.3389/fmicb.2019.02270

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Copyright © 2019 Felczak, Jacobson, Ong, Amador-Noguez and TerAvest.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Simplified schematic of the EMP (left) and ED (right) pathways of glycolysis. Pfk, Fba, and Tpi reactions are indicated in red because heterologous expression of these enzymes was the major genetic change made in this study. Abbreviations: DHAP, dihydroxyacetone phosphate; KDPG, 2-keto-3-deoxy-6-phosphogluconate; Pfk, phosphofructokinase; Fba, fructose bisphosphate aldolase; Tpi, triosephosphate isomerase. The arrows show the directions of the flux through EMP or ED pathways and do not reflect reversibility/irreversibility of the reactions.