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. 2019 Sep 27;10:2280. doi: 10.3389/fimmu.2019.02280

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Copyright © 2019 Coronado, Zakzuk, Regino, Ahumada, Benedetti, Angelina, Palomares and Caraballo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inhibition of IL-10 signaling pathway reduces the effect of rAl-CPI on humoral response against Blomia tropicalis. (A) Total number of eosinophils and neutrophils in BAL. (B) Cytokine levels BAL, IL-10, IL-5, and IL-10. (C) Serum Total IgE, IgG1, and BtE allergen-specific IgE, IgG1, and IgG2a antibody levels. The mean values ± SEM are shown for 5–6 mice per group when the anti-IL-10R monoclonal was used. One-way ANOVA + Bonferroni for post-hoc comparisons). ^*p ≤ 0.05; ^**p ≤ 0.01, ^***p ≤ 0.001.