Fig. 1.

a Microdeletion at 14q21.2 (chr14:43545282-43837068 according to hg19), detected in the proband, is highlighted in yellow, whereas LRFN5 (chr14:42076764-42373752), at 1.12 Mb distance, is highlighted in the light blue area. b Expression levels of LRFN5 in the proband (P), his father (F) and controls (CTRLs) (n = 7) were significantly reduced in the proband and his father (**p < 0.001, *p < 0.005). c Expression levels of chr14.232.a in the proband (P), his father (F) and controls (CTRLs) (n = 5) were significantly reduced in the proband (*p < 0.05)